Will My ASP.NET 1.1 Value Applications Function if I Enable the ASP.NET 2.0 Runtime?
If you are running ASP.NET 1.1 versions of the value applications Dot Net Nuke or Community Server, you can enable the ASP.NET 2.0 runtime without impacting these applications as long as any ASP.NET 2.0 applications are uploaded to a custom directory and not the root of your hosting account.
If you are running ASP.NET 2.0 versions of the above applications, no potential conflict exists.